Comparison of latent tuberculosis infection rate between contacts with active tuberculosis and non-contacts

Evaluation and Comparison of Body Mass Index and Albumin Level in Patients with Active Tuberculosis and Latent Tuberculosis Infection

Introduction: Limited data are available on the relationship between nutritional status and tuberculosis. The aim of this study was to evaluate and compare the body mass index (BMI) and serum albumin level in patients with active tuberculosis (ATB) and latent tuberculosis (LTB). Materials and Methods: A cross-sectional study was conducted on 17 patients newly diagnosed with pulmonary TB  who we...

Evaluation of Interleukin17and Interleukin 23 expression in patients with active and latent tuberculosis infection

Objective(s): Tuberculosis is one of the most important infectious diseases with high mortality rates worldwide, especially in developing countries. Interleukin17 (IL-17) is an important acquired immunity cytokine, which is mainly produced by CD4+TH17 cells. It can recruit neutrophils and macrophages to the infected site in the lungs. IL-23 is one of the most important inducers of IL-17. In the...

Tuberculosis contacts and prophylaxis.

Risk factors for latent tuberculosis infection in close contacts of active tuberculosis patients in South Korea: a prospective cohort study

BACKGROUND The diagnosis and treatment of latent tuberculosis infection (LTBI) have become mandatory to reduce the burden of tuberculosis worldwide. Close contacts of active TB patients are at high risk of both active and LTBI. The aim of this study is to identify the predominant risk factors of contracting LTBI, persons in close contact with TB patients were recruited. This study also aimed to...

What Patient Factors Predict Physicians’ Decision Not to Treat Latent Tuberculosis Infection in Tuberculosis Contacts?

OBJECTIVE The study aimed to determine factors that are associated with physicians' decision to offer treatment for latent tuberculosis infection (LTBI) in contacts of patients with tuberculosis. METHODS We performed a nested case-control study in a cohort of contacts of patients with pulmonary tuberculosis who had a tuberculin skin test (TST) ≥ 10 mm. Cases were those who were offered treatm...